At least seven people were killed and another 22 injured on Tuesday when a tour bus heading for Iguazu Falls overturned in the southern Brazilian state of Parana, police said.
According to Parana's Federal Highway Police, the bus carrying 54 persons had departed from Florianopolis, capital of Santa Catarina state, on its way further south to Foz do Iguacu, a Brazilian town bordering Argentina and Paraguay.
Among the fatal victims were an Argentine mother and her three-year-old daughter, the local fire department told reporters.
Local authorities have opened an investigation to determine the cause of the accident.
A surviving passenger, Alexandro de Oliveira Gamaro, said he spoke with the bus driver after the crash and the driver admitted to having fallen asleep.